MİKROSÜNGER TAŞIYICI SİSTEMLER : MICROSPONGE DELIVERY SYSTEMS
نویسندگان
چکیده
منابع مشابه
An Overview on Microsponge Delivery System
Microsponge were prepared by liquid-liquid suspension polymerization of styrene and methyl methacrylate. Microsponges were dispersed in gel prepared by using carbopol 940 and evaluated for drug release using Franz diffusion cell. Free flowing powder with size distribution 30 to 107 μm was obtained. The average drug release from the gels containing microspongic fluconazole was 67.81% in 12 h. dr...
متن کاملFormulation and Evaluation of Microsponge Drug Delivery System Using Indomethacin
In the present study controlled release formulation of Indomethacin microsponges were prepared by using Eudragit RS 100, pH independent release retardant polymer and PVA, stabilizer or emulsifier. Microsponges were prepared by Quasi emulsion solvent diffusion method by changing drug polymer ratio (3:1, 4:1, 5:1) and process was optimized. Microsponges were evaluated by micromeritic properties, ...
متن کاملMicrosponge Delivery System (mds): a Unique Technology for Delivery of Active Ingredients
In pharmaceutical industry, various controlled released dosage forms like solid formulation, semi solid formulation and topical preparation have more importance due to efficacy and patient compliance. Topical preparations have some disadvantages like unpleasant odour, greasiness and skin irritation and fail to reach the systemic circulation in sufficient amounts in few cases. This problem is ov...
متن کاملThe microsponge delivery system of Acyclovir: Preparation, characterization and in-vitro evaluation
The aim of the present study was to develop and evaluate microsponge based topical delivery system of acyclovir for sustained and enhanced drug deposition in the skin. Microsponges containing acyclovir were prepared by an emulsion solvent diffusion method. The effect of formulation variable such as drug: polymer ratio, stirring speed, internal phase on the physical characteristics of microspong...
متن کاملFormulation and In-Vitro Evaluation of Fluconazole Loaded Microsponge Gel For Topical Sustained Delivery
The objective of present work was to formulate and evaluate Fluconazole (FLZ) microsponges using quasi emulsion solvent diffusion technique and microsponge gel by using carbopol. Microsponges containing FLZ were obtained successfully with different proportions of ethyl cellulose polymer (EC). The formulations were studied for particle size and physical characterization. The physical characteriz...
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ژورنال
عنوان ژورنال: Ankara Universitesi Eczacilik Fakultesi Dergisi
سال: 2000
ISSN: 1015-3918
DOI: 10.1501/eczfak_0000000349